Pragmatic trials are a transformative approach in clinical research designed to integrate real-world data into clinical trials. They aim to bridge the gap between clinical research and practice by ensuring that trial results are applicable to broader, real-world populations. Here are some key aspects of pragmatic trials: Real-world applicability: Pragmatic trials are designed to determine whether a therapy works in diverse, real-world settings, addressing a question often unanswered by traditional randomized controlled trials (RCTs) due to their controlled nature and homogeneous populations. Flexibility: Pragmatic trials offer flexibility by allowing the integration of existing data and the enrollment of diverse populations … Continue reading What are Pragmatic Trials?