Hyperbaric Oxygen Therapy Shows Promise for Long-Term PTSD
In a reanalysis of a prior trial in 56 male veterans with treatment‑resistant PTSD, participants who achieved at least...
World’s First Self-Regulating Immunotherapy Trial Launches
The UK’s MHRA has granted Clinical Trial Authorisation for NVG-222, clearing a first-in-human, Phase I/II adaptive basket study in...
Tonix Licenses Phase 2/3-Ready Antibody for Lyme Prevention
Phase 1 data for TNX-4800 (mAb 2217LS) showed safety and tolerability with a linear pharmacokinetic:pharmacodynamic: efficacy relationship, supporting dose...
Landmark Vivos Trial Treats Pediatric Obstructive Sleep Apnea
A multicenter pediatric trial of Vivos Therapeutics’ DNA (Daytime-Nighttime Appliance) reported that 77% of participants achieved at least a...
Rein Therapeutics Publishes Novel IPF Therapy Data in iScience
Ex vivo human IPF lung slices exposed to LTI-03 showed reductions across TGFβ, VEGF, PDGF, and FGF signaling, along...
Hope for AMD: Kalaris Enrolling New Phase 1/2 Drug Trial
No efficacy or safety data were released. Kalaris has begun enrolling a Phase 1b/2 multiple ascending dose study of...
First Real-World Study Reveals Patient Experience on Sympazan
In a retrospective EHR cohort spanning 2015–2024, Stanford Health Care identified 181 patients with epilepsy treated with clobazam oral...
Kalaris Launches Promising New Trial for Macular Degeneration
Kalaris has opened enrollment for a Phase 1b/2 multiple-ascending-dose study of TH103 in neovascular AMD, targeting up to 80...
Spyre Doses First Patient in Phase 2 Rheumatic Disease Trial
Spyre Therapeutics has dosed the first patient in SKYWAY, a randomized, placebo-controlled Phase 2 basket trial of SPY072, an...
What Happened In The Efzofitimod Sarcoidosis Phase 3 Study
Efzofitimod missed the primary endpoint in the Phase 3 EFZO-FIT study, reducing mean daily oral corticosteroid dose at week...