Vadadustat Shows Favorable Mortality, Hospitalization Data
In a post-hoc win-odds analysis of the Phase 3 INNO2VATE program, vadadustat (Vafseo) outperformed darbepoetin alfa on a hierarchical...
ProKidney Presents Full Phase 2 Rilparencel Trial Results
In a Phase 2 open-label study of patients with advanced CKD and diabetes, bilateral renal injections of rilparencel improved...
Atacicept Delivers Remarkable Phase 3 Data for IgA Nephropathy
At 36 weeks, atacicept delivered a 46% reduction from baseline in 24-hour urine protein-to-creatinine ratio and a 42% reduction...
Chemomab Announces New Nebokitug PSC Data at Liver Meeting
Nebokitug maintained favorable safety and sustained biomarker improvement through 48 weeks in the Phase 2 SPRING open-label extension in...
Annovis Alzheimer’s Program Sees Strong Phase 3 Progress
All 84 U.S. sites are active for Annovis Bio’s pivotal Phase 3 Alzheimer’s program, with the first participants reaching...
Promising Barzolvolimab Data Shows Complete Urticaria Control
Celldex’s barzolvolimab delivered a mean UCT7 improvement of up to 8.6 points versus 2.5 for placebo at Week 12...
Avance Unveils Special CNS Center for Neuroscience Trials
Screen failure rates average 57% in CNS studies, compared with 36.3% across other therapeutic areas, and Avance Clinical points...
Quoin Netherton Syndrome Study Shows Positive 9-Month Data
In an investigator-led pediatric study of QRX003 for Netherton syndrome, the first enrolled child achieved complete skin clearance by...
Hutchmed Completes Enrollment for Saffron Lung Cancer Trial
HUTCHMED and AstraZeneca completed randomization of 338 patients in SAFFRON, a global, open-label Phase III comparing all-oral savolitinib plus...
Mesoblast to Meet FDA on Rexlemestrocel-L for Opioid Use
In a randomized Phase 3 study of 404 patients with discogenic chronic low back pain, including 168 on opioids...