The Bispecific Combination Wave Is Here: What the Englumafusp-Glofitamab Trial Signals for Hematology Trial Design
A Phase 1 trial pairing englumafusp alfa with glofitamab in B-cell NHL reveals a mechanistic shift reshaping how sponsors...
After EVAR, the Aneurysm Sac Remains. Shape Memory Medical Is Running the First Randomized Pivotal Trial to Do Something About It.
With enrollment complete at 48 centers across three countries, CEO Ted Ruppel and VP of Marketing Mary Dennehy explain...
RT-114 Achieves Oral Bioavailability Exceeding Subcutaneous Dose in Phase 1a
RT-114 oral bioavailability exceeded subcutaneous dosing by over 150% in Phase 1a, marking a significant advance for GLP-1 delivery.
Allogene’s ALLO-316 Achieves 31% Response Rate in Advanced Renal Cell Carcinoma
ALLO-316 achieves 31% response rate in advanced renal cell carcinoma patients previously resistant to checkpoint inhibitors and tyrosine kinase...
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Your Recruitment Plan Is Failing Before Screening Even Starts
59% of sites report recruitment blocked by process inefficiencies—the bottleneck isn't patient supply, it's the workflow that never gets...
SCI-110’s Phase IIb in Tourette Syndrome: What Hannover Tells Us About Cannabinoid Trial Design in CNS
NeuroThera Labs activates Hannover Medical School for SCI-110 Phase IIb in adult Tourette Syndrome, building on a 21% tic...
When the Site Is Also the Sponsor: Princess Máxima’s Rinke Riezebos on Data Standardization, Protocol Design, and Why Sponsors Should Listen to Their Sites
Princess Máxima Center for Pediatric Oncology is both sponsor and site, and that dual vantage point gives Rinke Riezebos...
59% of Clinical Trial Sites Losing Eligible Patients to Process Inefficiencies
59% of clinical trial sites lose eligible patients due to process inefficiencies rather than patient scarcity, revealing a throughput...
ORIC Initiates Himalayas-1 Phase 3 Trial of Rinzimetostat for mCRPC
ORIC initiates Himalayas-1 Phase 3 trial of rinzimetostat plus darolutamide in 600 mCRPC patients previously treated with abiraterone.
Hemab’s Sutacimig Cuts Bleeds 84% in Phase 2 Glanzmann Thrombasthenia Study
Hemab's sutacimig cut treated bleeds 84% in Phase 2 Glanzmann Thrombasthenia study, advancing weekly subcutaneous prophylaxis toward Phase 3...