Upstream Bio Caps COPD Study, Redirects to Phase 3 Design
Upstream Bio caps COPD Study enrollment at 400 participants and pivots to Phase 3 design around quarterly dosing for...
Voyager’s VY1706 cuts tau 64% in primates with no safety issues
Voyager's VY1706 achieves 64% tau reduction in primates with no safety issues, clearing preclinical path for human trials later...
Oruka Reports 63.5% PASI 100 Rate for ORKA-001 at Week 16 in Psoriasis
Oruka's ORKA-001 achieves 63.5% PASI 100 rate at Week 16 in psoriasis, exceeding typical IL-23 inhibitor performance at midpoint...
Avalo’s abdakibart achieves 42.5% HiSCR75 response in hidradenitis suppurativa trial
Avalo's abdakibart achieves 42.5% HiSCR75 response in hidradenitis suppurativa trial, the highest absolute improvement reported in comparable Phase 2...
Oral semaglutide achieves 21.6% weight loss in early responders, doubles mobility gains
Oral semaglutide achieves 21.6% weight loss in early responders and nearly doubles mobility gains versus placebo in OASIS 4...
ICON’s San Antonio Expansion Looks Like Opportunity—Your IRB Timeline Says Otherwise
ICON opens early-phase units in San Antonio, Houston, and Lawrence, KS—but sponsors activating satellite clinics face IRB, contract, and...
Zentalis’s Azenosertib Strategy Hinges on DENALI Phase 2 Data
Zentalis's azenosertib strategy depends on DENALI Phase 2 data readout expected before year-end 2026 in Cyclin E1-positive ovarian cancer...
Capricor Sues Distributor NS Pharma Over Deramiocel Deal Structure
Capricor sues NS Pharma over deramiocel deal structure, claiming the pricing model prevents Medicare and Medicaid coverage ahead of...
Ajax Presents Phase 1 Data for Type II JAK2 Inhibitor AJ1-11095 at EHA
Ajax's type II JAK2 inhibitor AJ1-11095 shows early VAF reduction in Phase 1 data for myelofibrosis patients who failed...
Foundayo Maintains Weight Loss in Lilly Trial After Injectable Switch
Foundayo maintained weight loss in Lilly's ATTAIN-MAINTAIN trial after patients switched from Wegovy, losing only 0.9 kg over 52...