Benitec BB-301 Trial Shows Positive Long-Term Efficacy
Topline data: In Benitec’s Phase 1b/2a OPMD study, the first treated patient showed sustained and deepening benefit at 24...
eClinical Tech News
Phase 1 Trial of AGENT-797 to Prevent Graft-vs-Host Disease
MiNK Therapeutics will open an investigator-sponsored Phase 1 trial of its off-the-shelf iNKT cell therapy, agenT-797, in allogeneic hematopoietic...
ALX Oncology Advances Trials for Evorpacept and ALX2004
No dose-limiting toxicities have been observed to date in ALX Oncology’s first-in-human study of its EGFR-targeted ADC ALX2004, which...
ACTG Launches iPACE-HIV Study on Frailty Intervention
ACTG has opened enrollment for A5426 (IPACE-HIV), a Phase 2, double-blind, randomized study testing the senolytic combination of dasatinib...
Regenera Device May Transform Breast Reconstruction After Trial
Topline data: In a 94-patient pivotal trial in lumpectomy patients receiving adjuvant therapy, Tensive’s REGENERA bioresorbable scaffold met its...
Pulmocide Terminates Phase 3 Opera-T Study of Opelconazole
Interim data from Opera-T showed a numerically lower Day 84 favorable response rate and a numerically higher mortality rate...
Pridcor Long COVID Study Hits FDA & Publication Milestones
An observational case series published in Frontiers in Immunology reports sustained, patient-reported improvements in core Long COVID symptoms—fatigue, dysautonomia,...
New Hope in Trial for Difficult-to-Treat Pediatric Cancers
Two complete metabolic responses in relapsed/refractory metastatic Ewing sarcoma and one complete response in relapsed/refractory metastatic neuroblastoma headline the...
Ernexa’s Promising Cancer Trial Advances with FDA Success
Ernexa Therapeutics has completed a Pre-IND meeting with FDA and is targeting an IND submission to support a first-in-human...
MindRank’s Promising AI Oral GLP-1 Enters Phase III Trial
MindRank’s Phase IIb data for MDR-001 showed a 10.3% mean weight reduction at Week 24 in 317 participants, with...