AIM Plans Pivotal Phase 3 Trial for Pancreatic Cancer
In late-stage pancreatic ductal adenocarcinoma, rintatolimod (Ampligen) has generated early clinical signals across multiple settings: a Dutch named-patient program...
eClinical Tech News
Surging Storm Therapeutics Secures $56M for Sarcoma Drug
In earlier-stage testing, STC-15, an oral METTL3 inhibitor, produced durable tumor regressions across multiple sarcoma subtypes as monotherapy. Building...
COACH trial: hGH accelerates CNP benefits in achondroplasia
At Week 52 in the Phase 2 COACH trial, once-weekly TransCon CNP plus once-weekly TransCon hGH delivered a mean...
Pioneering gammaCore nVNS Study for PTSD Enrolls First Patient
electroCore’s gammaCore non-invasive vagus nerve stimulation device has entered PTSD clinical testing with the first eight of a planned...
Landmark Study Validates AI for Opioid Disorder Treatment
A peer-reviewed study in PNAS reports that GATC-1021, an AI-identified small molecule modulating 5-HT2A and 5-HT6 receptors, reduced fentanyl...
Nervgen’s Successful FDA Meeting Sparks Phase 3 Trial Hope
NVG-291 produced a mean 3.7-point gain on GRASSP Quantitative Prehension at Week 12 in chronic tetraplegia versus 0.4 points...
Trethera & MGH Launch Clinical Trial for TRE-515 in ALS
In Trethera’s prior expanded access case, treatment with TRE-515 in an 87-year-old patient with advanced ALS was associated with...
Ernexa Therapeutics Advances Toward 2026 Human Trials
Preclinical data from a syngeneic ovarian cancer model showed that Ernexa’s ERNA-101, an engineered induced mesenchymal stem cell therapycell...
Adagene, Incyte Collaborate on Colorectal Cancer Drug Trial
No new efficacy data accompanied the announcement. Prior signals for the components remain preliminary: muzastotug has shown encouraging responses...
Improved Durability Seen for Muzastotug Combo in CRC Study
Topline data from Adagene’s Phase 1b/2 trial in late-line MSS metastatic colorectal cancer without liver metastases show a dose-dependent...