SAPU003 Trial: Full Everolimus Bioavailability for Cancer
Oral everolimus delivers roughly 10% bioavailability; Sapu003, an intravenous formulation, is designed to bypass absorption limits and deliver full...
Jon Napitupulu
DSMB Recommends Seastar Medical Continue Pivotal AKI Trial
Zero device-related adverse events were observed among the first 100 adult patients in SeaStar Medical’s NEUTRALIZE-AKI pivotal trial of...
New Drug Shows 86% Survival in Pancreatic Cancer Patients
Topline: In a single-arm Phase 2a cohort (N=34) of first-line pancreatic cancer, atebimetinib (IMM-1-104) plus modified gemcitabine/nab-paclitaxel delivered 86%...
Briumvi Data: Remarkable Halt to MS Disability Progression
Year 6 data from the ULTIMATE I & II open-label extensions showed an annualized relapse rate of 0.012 on...
Akari’s Novel ADC Payload Shows Potential in Preclinical Data
In preclinical models, Akari’s spliceosome-modulating ADC payload, PH1, suppressed AR-V7 expression in 22Rv1 metastatic castration-resistant prostate cancer cells and...
Sapu003 Trial Delivers New Hope for Breast Cancer Patients
Sapu Nano received Human Research Ethics Committee approval in Australia to initiate a Phase 1 study of Sapu003, an...
Promising New Partnership Targets Triple-Negative Breast Cancer
Cellectar Biosciences plans to initiate a Phase 1b study of CLR 125 in triple-negative breast cancer in the fourth...
Japan Approves Burning Rock Test for Breast Cancer Drug
Japan’s Ministry of Health, Labour and Welfare has granted Manufacturing and Marketing Approval to the OncoGuide OncoScreen Plus CDx...
Breakthrough: Synendos Phase 1 Results Boost Mental Health
In a completed Phase 1 program, SYT-510 was administered to 60 healthy volunteers across single- and multiple-ascending dose cohorts...
Trethera Awarded $1.8M Grant for Crohn’s Drug Development
Trethera secured a $1.8 million NIH award to advance preclinical studies of TRE-515 in Crohn’s disease, following a prior...